Detailed Notes on megatomi.com
Detailed Notes on megatomi.com
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Quickly attain sections as thin or thick as your application calls for, without worrying about dropping or distorting worthwhile tissue samples.
Megatome can be a vibrating microtome built to portion a broad choice of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With superior blade vibrating frequency and minimized blade deflection, Megatome enables significant-throughput tissue sectioning with uniform area profile, and minimal tissue harm and information reduction.
Antibodies may well acquire months to diffuse by only some millimeters of tissue, that has a steep labeling gradient from floor to Main.
Megatome is created for precision: the blade vibrates at a better frequency and bigger amplitude assortment than other microtomes, and incorporates a special deflection Handle mechanism.
SE uses a rotational electric powered industry to disperse remarkably electromobile molecules (for example antibodies or surfactant micelles) through a porous sample with no harmful electrically charged buildings throughout the tissue. This permits 2-4 working day clearing of intact organs,
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Megatome is often a novel microtome that permits for top-precision sectioning of a wide array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with negligible tissue injury and information reduction.
eFLASH is really a immediate tissue labeling procedure that permits for uniform whole-organ staining in twenty rounds of labeling.
The SmartSPIM light sheet microscope delivers unparalleled resolution and acquisition speed all over intact tissue volumes, although its modular structure lets you upgrade and personalize individual parts.
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Defend avoids the variability of hydrogel embedding and the data loss from PFA preservation, safeguarding specimens for various rounds of processing.
Leverage the Clear+ tissue clearing technique, as well as eFLASH and patented stochastic electrotransport systems, to speedily apparent and label whole organs. Crucial highlights and characteristics include things like:
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